Evidence for isomerization during binding of apolipoprotein-B100 to low density lipoprotein receptors.
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چکیده
منابع مشابه
Evidence for isomerization during binding of apolipoprotein-B100 to low density lipoprotein receptors.
To determine the kinetics of human low density lipoproteins (LDL) interacting with LDL receptors, 125I-LDL binding to cultured human fibroblasts at 4 degrees C was studied. Apparent association rate constants did not increase linearly as 125I-LDL concentrations were increased. Instead, they began to plateau which suggested that formation of initial receptor-ligand complexes is followed by slowe...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)48489-x